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Internal fat may be the leading cause of heart failure, study finds

Internal fat may be the leading cause of heart failure, study finds
health9/3/2025

Heart failure with preserved ejection fraction, or HFpEF, has puzzled doctors for years. Nearly four million Americans and more than 30 million people worldwide live with this condition, yet treatment options remain limited.

A new theory suggests signals from fat tissue, not just the heart, may drive a common type of heart failure. (CREDIT: Shutterstock) Heart failure with preserved ejection fraction, or HFpEF, has puzzled doctors for years. Nearly four million Americans... [8041 chars]